Paper in Nature Ecology and Evolution


Nature Ecology and Evolution paper on ancient genome architecture by Bob Zimmermann, Nicolas Robert, Ulrich Technau and Oleg Simakov

The level of conservation of ancient metazoan gene order (synteny) is remarkable. Despite this, the functionality of the vast majority of such regions in metazoan genomes remains elusive. Utilizing recently published single-cell expression data from several anciently diverging metazoan species, we reveal the level of correspondence between cell types and genomic synteny, identifying genomic regions conferring ancient cell type identity.

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